Meet The Research Team
The Endocrine Oncology Research Group is headed by Dr Leonie Young and is based at York House, RCSI, St Stephen’s Green, Dublin. Dr Young graduated from Trinity College Dublin, and in 1997 completed her PhD training at University College Dublin.
Dr Ann Hopkins is based in the RCSI Education and Research Centre in Beaumont Hospital, Dublin. Dr Hopkins received her PhD in Pharmacology from University College Dublin, and spent several years working in the Epithelial Pathobiology Research Unit in Emory University, Atlanta, USA, before returning to Ireland in 2004.
“As a senior research technician, I am responsible for overseeing the daily operations of the lab, including equipment, lab personnel and supplies. In addition, I am involved in the construction of tissue microarrays and biomarker staining, which provides a robust resource to determine how our proteins of interest correlate with clinicopathological parameters.”
“My research is focused on identifying and analyzing the gene network involved in the development of endocrine resistance. In particular, I am looking at developing new therapeutic targets and biomarkers of response to therapy for ER-positive metastatic breast cancer. I am currently funded by Breast Cancer Ireland.”
“My research focuses on tumour heterogeneity in endocrine-resistant breast cancer. Specifically, I am looking at different cell types and their potential to spread or metastasize to other parts of the body. I am currently funded by Science Foundation Ireland.”
“As senior research technician in the Endocrine Oncology Group, my main duty is to contribute towards the development of both on-going research and new research projects. Some of my responsibilities include managing the daily running of the lab, training and troubleshooting molecular techniques within the group, and project managing the biomedical research aspect for our team.”
“My research is focused on analysing large scale transcriptomic datasets to find aberrant patterns of gene expression driving metastatic breast cancer. Currently, I am applying correlation network analysis to RNA sequencing data from patient-matched primary breast and distant metastatic tumour samples. Funding is provided by Breast Cancer Ireland.”
“I am interested in understanding why a significant portion of patients do not see the same efficacy with the current hormone treatments. My research is interested in merging pre-clinical work with genomic profiling of cancer tissue to better understand the mechanisms of disease recurrence, and help us devise effective strategies to overcome it.”
“My current research focuses on investigating the clinical potential of receptor tyrosine kinases as therapeutic targets in breast cancer brain metastasis. Funding is provided by Breast Cancer Ireland.”