Jason McGrath

Jason McGrath is a postdoctoral cancer researcher whose work focuses on understanding why some breast cancers become more difficult to treat, particularly when the disease spreads to the brain.

Using tumour samples donated by patients alongside sophisticated laboratory models, Jason studies metastatic breast cancer to identify weaknesses that could potentially be targeted by treatment.

A major part of his research examines how cancer cells repair damage to their DNA. Some cancer cells are less capable of repairing this damage, which may make them vulnerable to particular treatments.

Jason is investigating whether PARP inhibitors — drugs already used to treat certain breast cancers — could potentially benefit some patients whose breast cancer has spread to the brain and whose tumours have specific DNA-repair weaknesses.

Why This Research Matters

Finding a weakness in a cancer cell can create an opportunity to target it. Jason’s research could help identify patients with brain metastases who may benefit from targeted treatments, potentially creating new treatment options where they are urgently needed.

Research gives us the power to turn what we learn about cancer into better treatment possibilities. That is how we Rewrite the Future